Tioxolone

Tioxolone is an inhibitor of carbonic anhydrase I. It is selective for CAI over CAII, -III, -IV, -VA, -VB, -VI, -VII, -IX, -XII, and -XIV. Tioxolone is active against Gram-positive or -negative bacteria, including M. tuberculosis. It is also active against dermatophytes, yeasts, and molds.

Product information

CAS Number: 4991-65-5

Molecular Weight: 168.17

Formula: C7H4O3S

Synonym:

Acnosan

Tioxolon

Chemical Name: 6-hydroxy-2H-1,3-benzoxathiol-2-one

Smiles: OC1=CC2OC(=O)SC=2C=C1

InChiKey: SLYPOVJCSQHITR-UHFFFAOYSA-N

InChi: InChI=1S/C7H4O3S/c8-4-1-2-6-5(3-4)10-7(9)11-6/h1-3,8H

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Solubility: DMSO : ≥ 100 mg/mL (594.64 mM)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 ^oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 ^oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

References:

1. Maryam Hakimi Parizi, et al. Tioxolone niosomes exert antileishmanial effects on Leishmania tropica by promoting promastigote apoptosis and immunomodulation. Asian Pacific Journal of Tropical Medicine 2019; 12(8): 365-374.

Products are for research use only. Not for human use.