详情描述
Taltirelin is a thyrotropin-releasing hormone analog. Taltirelin alleviates mechanical allodynia through activation of descending monoaminergic neurons in persistent inflammatory pain.
Product information
CAS Number: 103300-74-9
Molecular Weight: 405.41
Formula: C17H23N7O5
Synonym:
TA0910
TA-0910
TA 0910
Ceredist
Chemical Name: (4S)-N-[(2S)-1-[(2S)-2-carbamoylpyrrolidin-1-yl]-3-(1H-imidazol-5-yl)-1-oxopropan-2-yl]-1-methyl-2,6-dioxo-1,3-diazinane-4-carboxamide
Smiles: CN1C(=O)N[C@@H](CC1=O)C(=O)N[C@@H](CC1=CN=CN1)C(=O)N1CCC[C@H]1C(N)=O
InChiKey: LQZAIAZUDWIVPM-SRVKXCTJSA-N
InChi: InChI=1S/C17H23N7O5/c1-23-13(25)6-10(22-17(23)29)15(27)21-11(5-9-7-19-8-20-9)16(28)24-4-2-3-12(24)14(18)26/h7-8,10-12H,2-6H2,1H3,(H2,18,26)(H,19,20)(H,21,27)(H,22,29)/t10-,11-,12-/m0/s1
Technical Data
Appearance: Solid Power
Purity: ≥98% (or refer to the Certificate of Analysis)
Solubility: DMSO : 100 mg/mL (246.66 mM; Need ultrasonic)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life: ≥12 months if stored properly.
Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.
Drug Formulation: To be determined
HS Tariff Code: 382200
References:
- Thirunarayanan N, et al. Taltirelin is a superagonist at the human thyrotropin-releasing hormone receptor. Front Endocrinol (Lausanne). 2012 Oct 9;3:120.
Products are for research use only. Not for human use.