详情描述
DMOG, also known as Dimethyloxaloylglycine, is a cell permeable, competitive inhibitor of HIF-PH. It acts to stabilize HIF-1α expression at normal oxygen tensions in cultured cells, at concentrations between 0.1 and 1 mM. DMOG provides neuroprotection after traumatic brain injury. DMOG provides enhanced efficacy with reduced systemic exposure in a murine model of colitis.
Product information
CAS Number: 298-96-4
Molecular Weight: 334.80
Formula: C19H15ClN4
Synonym:
TTC
TPTZ
2,3,5-Triphenyltetrazolium chloride
Chemical Name: triphenyl-3H-1,2λ⁵,3,4-tetrazol-2-ylium chloride
Smiles: [Cl-].C1=CC=CC=C1C1N=[N+](C2C=CC=CC=2)N(N=1)C1C=CC=CC=1
InChiKey: PKDBCJSWQUOKDO-UHFFFAOYSA-M
InChi: InChI=1S/C19H15N4.ClH/c1-4-10-16(11-5-1)19-20-22(17-12-6-2-7-13-17)23(21-19)18-14-8-3-9-15-18;/h1-15H;1H/q+1;/p-1
Technical Data
Appearance: Solid Power
Purity: ≥98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life: ≥12 months if stored properly.
Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.
Drug Formulation: To be determined
HS Tariff Code: 382200
Products are for research use only. Not for human use.