详情描述
SBE13 is a potent and selective Plk1 inhibitor, with an IC50 of 200 pM; SBE13 poorly inhibits Plk2 (IC50>66 μM) or Plk3 (IC50=875 nM).
Product information
CAS Number: 775294-82-1
Molecular Weight: 442.94
Formula: C24H27ClN2O4
Synonym:
SBE-13
Chemical Name: ({4-[(6-chloropyridin-3-yl)methoxy]-3-methoxyphenyl}methyl)[2-(3,4-dimethoxyphenyl)ethyl]amine
Smiles: COC1=CC=C(CCNCC2C=C(OC)C(=CC=2)OCC2=CN=C(Cl)C=C2)C=C1OC
InChiKey: XNPRQBVQOJZMMA-UHFFFAOYSA-N
InChi: InChI=1S/C24H27ClN2O4/c1-28-20-7-4-17(12-22(20)29-2)10-11-26-14-18-5-8-21(23(13-18)30-3)31-16-19-6-9-24(25)27-15-19/h4-9,12-13,15,26H,10-11,14,16H2,1-3H3
Technical Data
Appearance: Solid Power
Purity: ≥98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life: ≥12 months if stored properly.
Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.
Drug Formulation: To be determined
HS Tariff Code: 382200
Products are for research use only. Not for human use.