Catalog No. Size 价格库存数量
S4610-2 Solid 2 mg ¥105
S4610-10 Solid 10 mg ¥315


M-110 is a inhibitor of protein arginine N-methyltransferases (PRMTs). It is also a highly isoform-selective, cell permeable and potent ATP-competitive inhibitor of the PIM kinase family that prefers PIM-3, shown to inhibit the proliferation of prostate cancer cell lines with IC50s between 0.6 to 0.9 μM, with no activity on normal human peripheral blood mononuclear cells up to 40 μM.

Product information

CAS Number: 1395048-49-3

Molecular Weight: 445.94

Formula: C22H28ClN5O3

Chemical Name: N'-[(1E)-1-(4-chloro-2-hydroxyphenyl)propylidene]-2-{[3-(morpholin-4-yl)propyl]amino}pyridine-4-carbohydrazide

Smiles: CC/C(=N\NC(=O)C1=CC(NCCCN2CCOCC2)=NC=C1)/C1=CC=C(Cl)C=C1O


InChi: InChI=1S/C22H28ClN5O3/c1-2-19(18-5-4-17(23)15-20(18)29)26-27-22(30)16-6-8-25-21(14-16)24-7-3-9-28-10-12-31-13-11-28/h4-6,8,14-15,29H,2-3,7,9-13H2,1H3,(H,24,25)(H,27,30)/b26-19+

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

Products are for research use only. Not for human use.


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