详情描述
TL13-112 shows chemically induced degradation of anaplastic lymphoma kinase (ALK).
Product information
CAS Number: 2229037-19-6
Molecular Weight: 1002.57
Formula: C49H60ClN9O10S
Chemical Name: N-(2-(2-(2-(4-(4-((5-Chloro-4-((2-(isopropylsulfonyl)phenyl)- amino)pyrimidin-2-yl)amino)-5-isopropoxy-2-methylphenyl)- piperidin-1-yl)ethoxy)ethoxy)ethyl)-2-((2-(2, 6-dioxopiperidin- 3-yl)-1, 3-dioxoisoindolin-4-yl)amino)acetamide
Smiles: CC1=CC(NC2=NC(NC3=CC=CC=C3S(=O)(=O)C(C)C)=C(Cl)C=N2)=C(C=C1C1CCN(CCOCCOCCNC(=O)CNC2=CC=CC3=C2C(=O)N(C2CCC(=O)NC2=O)C3=O)CC1)OC(C)C
InChiKey: XIRQUXILNXIWDI-UHFFFAOYSA-N
InChi: InChI=1S/C49H60ClN9O10S/c1-29(2)69-40-26-34(31(5)25-38(40)55-49-53-27-35(50)45(57-49)54-36-10-6-7-12-41(36)70(65,66)30(3)4)32-15-18-58(19-16-32)20-22-68-24-23-67-21-17-51-43(61)28-52-37-11-8-9-33-44(37)48(64)59(47(33)63)39-13-14-42(60)56-46(39)62/h6-12,25-27,29-30,32,39,52H,13-24,28H2,1-5H3,(H,51,61)(H,56,60,62)(H2,53,54,55,57)
Technical Data
Appearance: Solid Power
Purity: ≥98% (or refer to the Certificate of Analysis)
Solubility: DMSO: 50.13 mg/mL(50 mM).
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life: ≥12 months if stored properly.
Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.
Drug Formulation: To be determined
HS Tariff Code: 382200
Products are for research use only. Not for human use.