详情描述
Photo-lenalidomide-acid is a functionalized cereblon ligand containing a dimethoxy azo-benzene photoswitch; for use as a precursor to photoswitchable Degraders (PHOTACs). Photo-lenalidomide-acid is supplied with a carboxylic acid functional handle for ready conjugation to a linker/target protein ligand. Part of a range of functionalized tool molecules for Degrader R&D.
Product information
CAS Number: 2363154-39-4
Molecular Weight: 482.44
Formula: C23H22N4O8
Synonym:
Photo lenalidomide acid
Chemical Name: 2-{4-[(E)-2-[2-(2,6-dioxopiperidin-3-yl)-1-oxo-2,3-dihydro-1H-isoindol-4-yl]diazen-1-yl]-2,6-dimethoxyphenoxy}acetic acid
Smiles: COC1C=C(C=C(OC)C=1OCC(O)=O)/N=N/C1=CC=CC2=C1CN(C1CCC(=O)NC1=O)C2=O
InChiKey: CGLOIOJVUYAUAC-OCEACIFDSA-N
InChi: InChI=1S/C23H22N4O8/c1-33-17-8-12(9-18(34-2)21(17)35-11-20(29)30)25-26-15-5-3-4-13-14(15)10-27(23(13)32)16-6-7-19(28)24-22(16)31/h3-5,8-9,16H,6-7,10-11H2,1-2H3,(H,29,30)(H,24,28,31)/b26-25+
Technical Data
Appearance: Solid Power
Purity: ≥98% (or refer to the Certificate of Analysis)
Solubility: Soluble in DMSO
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life: ≥12 months if stored properly.
Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.
Drug Formulation: To be determined
HS Tariff Code: 382200
Products are for research use only. Not for human use.