SYP-5

SYP-5 is an inhibitor of Hypoxia-inducible factor-1 (HIF-1) that suppresses tumor cell migration and invasion, as well as tumor angiogenesis.

Product information

CAS Number: 1384268-04-5

Molecular Weight: 312.38

Formula: C18H16O3S

Chemical Name: (2E)-1-(5-hydroxy-2,2-dimethyl-2H-chromen-6-yl)-3-(thiophen-2-yl)prop-2-en-1-one

Smiles: CC1(C)C=CC2=C(O)C(=CC=C2O1)C(=O)/C=C/C1=CC=CS1

InChiKey: OMVURDVBYIJCOI-FNORWQNLSA-N

InChi: InChI=1S/C18H16O3S/c1-18(2)10-9-14-16(21-18)8-6-13(17(14)20)15(19)7-5-12-4-3-11-22-12/h3-11,20H,1-2H3/b7-5+

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Solubility: DMSO 62 mg/mL (198.48 mM)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 ^oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 ^oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

References:

1. Li-Hui Wang, et al. Eur J Pharmacol. 2016 Nov 15;791:560-568.

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