详情描述
SU5204 is a tyrosine kinase inhibitor with IC50 of 4 μM and 51.5 μM for FLK-1 (VEGFR-2) and HER2, respectively.
Product information
CAS Number: 186611-11-0
Molecular Weight: 265.31
Formula: C17H15NO2
Chemical Name: (3Z)-3-[(2-ethoxyphenyl)methylidene]-2,3-dihydro-1H-indol-2-one
Smiles: CCOC1=CC=CC=C1/C=C1\C(=O)NC2=CC=CC=C\12
InChiKey: MEZFKCPUSMBMAY-KAMYIIQDSA-N
InChi: InChI=1S/C17H15NO2/c1-2-20-16-10-6-3-7-12(16)11-14-13-8-4-5-9-15(13)18-17(14)19/h3-11H,2H2,1H3,(H,18,19)/b14-11-
Technical Data
Appearance: Solid Power
Purity: ≥98% (or refer to the Certificate of Analysis)
Solubility: DMSO : 100 mg/mL (376.92 mM; Need ultrasonic)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life: ≥12 months if stored properly.
Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.
Drug Formulation: To be determined
HS Tariff Code: 382200
References:
- Peng Cho Tang, et al. 3-heteroaryl-2-indolinone compounds for the treatment of disease. US5792783A.
Products are for research use only. Not for human use.