详情描述
R243 is an inhibitor of Chemokine (C-C motif) receptor 8 (CCR8) signaling and chemotaxis.
Product information
CAS Number: 688352-84-3
Molecular Weight: 357.44
Formula: C21H27NO4
Chemical Name: 7,8-Dihydro-7-[2-(tricyclo[3.3.1.1(3,7)]dec-1-yloxy)ethyl]-6H-1,3-dioxolo[4,5-g][1,3]benzoxazine
Smiles: C1C2=CC3OCOC=3C=C2OCN1CCOC12CC3CC(C1)CC(C2)C3
InChiKey: JJMLDSFDOODCIR-UHFFFAOYSA-N
InChi: InChI=1S/C21H27NO4/c1(2-26-21-8-14-3-15(9-21)5-16(4-14)10-21)22-11-17-6-19-20(25-13-24-19)7-18(17)23-12-22/h6-7,14-16H,1-5,8-13H2
Technical Data
Appearance: Solid Power
Purity: ≥98% (or refer to the Certificate of Analysis)
Solubility: DMSO: 71 mg/mL(198.63 mM).
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life: ≥12 months if stored properly.
Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.
Drug Formulation: To be determined
HS Tariff Code: 382200
References:
- Tomoyuki Oshio, et al. PLoS One. 2014 Apr 8;9(4):e94445.
Products are for research use only. Not for human use.