Catalog No. Size 价格库存数量
S0052-2 Contact for quotation ¥100
S0052-10 Contact for quotation ¥100


Propargyl-PEG2-amine is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Propargyl-PEG2-amine is a PEG-based PROTAC linker can be used in the synthesis of PROTACs.

Product information

CAS Number: 944561-44-8

Molecular Weight: 143.18

Formula: C7H13NO2

Chemical Name: 3-[2-(2-aminoethoxy)ethoxy]prop-1-yne



InChi: InChI=1S/C7H13NO2/c1-2-4-9-6-7-10-5-3-8/h1H,3-8H2

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Solubility: DMSO : 100 mg/mL (698.42 mM; Need ultrasonic).

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

How to use

In Vitro:

ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.


  1. Changchun Wang, et al. A kind of antibody coupling matter and its construction method containing boron ester units polymer. CN108721642A.
  2. Guangrong Zheng, et al. Bcl-2 proteins degraders for cancer treatment. WO2019144117A1.

Products are for research use only. Not for human use.


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