Praeruptorin A

Praeruptorin A is a main bioactive constituent of Peucedanum praeruptorum (also known as Bai-Hua Qian Hu). Praeruptorin A exerts anti-inflammatory effects in vitro through inhibition of NF-κB activation.

Product information

CAS Number: 73069-27-9

Molecular Weight: 386.40

Formula: C21H22O7

Chemical Name: [(9S, 10S)-10-acetyloxy-8, 8-dimethyl-2-oxo-9, 10-dihydropyrano[2, 3-f]chromen-9-yl] (Z)-2-methylbut-2-enoate

Smiles: C/C=C(/C)\C(=O)O[C@H]1[C@@H](OC(C)=O)C2=C3OC(=O)C=CC3=CC=C2OC1(C)C

InChiKey: XGPBRZDOJDLKOT-NXIDYTHLSA-N

InChi: InChI=1S/C21H22O7/c1-6-11(2)20(24)27-19-18(25-12(3)22)16-14(28-21(19,4)5)9-7-13-8-10-15(23)26-17(13)16/h6-10,18-19H,1-5H3/b11-6-/t18-,19-/m0/s1

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Solubility: To be determined

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 ^oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 ^oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

References:

1. Zhou X, et al. Effects of praeruptorin A and praeruptorin C, a racemate isolated from Peucedanum praeruptorum, on MRP2 through the CAR pathway. Planta Med. 2013 Nov;79(17):1641-7.

Products are for research use only. Not for human use.