SCD1 inhibitor-1

SCD1 inhibitor-1 is a potent and liver-selective stearoyl-CoA desaturase-1 (SCD1) inhibitor.

Product information

CAS Number: 1069094-65-0

Molecular Weight: 451.54

Formula: C21H22N3NaO3S2

Chemical Name: sodium 2-[2-(5-{[(2-butylphenyl)amino]methyl}thiophene-2-amido)-1,3-thiazol-4-yl]acetate

Smiles: CCCCC1=CC=CC=C1NCC1=CC=C(S1)C(=O)NC1=NC(CC(=O)O[Na])=CS1

InChiKey: XQNBRLFLBSUHOU-UHFFFAOYSA-M

InChi: InChI=1S/C21H23N3O3S2.Na/c1-2-3-6-14-7-4-5-8-17(14)22-12-16-9-10-18(29-16)20(27)24-21-23-15(13-28-21)11-19(25)26;/h4-5,7-10,13,22H,2-3,6,11-12H2,1H3,(H,25,26)(H,23,24,27);/q;+1/p-1

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Solubility: DMSO : 8.33 mg/mL (18.45 mM; Need ultrasonic).

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 ^oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 ^oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

References:

1. Iida T, et al. Discovery of potent liver-selective stearoyl-CoA desaturase-1 (SCD1) inhibitors, thiazole-4-acetic acid derivatives, for the treatment of diabetes, hepatic steatosis, and obesity. Eur J Med Chem. 2018 Oct 5;158:832-852.

Products are for research use only. Not for human use.