Ranaconitine

Ranaconitine is a diterpene alkaloid isolated from A. leucostomum, with cardiotoxicity.

Product information

CAS Number: 1360-76-5

Molecular Weight: 600.70

Formula: C32H44N2O9

Chemical Name: (2S, 3S, 4S, 5R, 6S, 8S, 13S, 16S, 17S)-11-ethyl-3, 8, 9-trihydroxy-4, 6, 16-trimethoxy-11-azahexacyclo[7.7.2.1, .0, .0, .0, ]nonadecan-13-yl 2-acetamidobenzoate

Smiles: CC(=O)NC1=CC=CC=C1C(=O)O[C@]12CN(CC)C3C4([C@@H]1CC3(O)[C@@]1(O)C[C@H](OC)[C@H]3C[C@@H]4[C@]1(O)[C@H]3OC)[C@H](CC2)OC

InChiKey: XTSVKUJYTUPYRJ-QQHZJSBHSA-N

InChi: InChI=1S/C32H44N2O9/c1-6-34-16-28(43-26(36)18-9-7-8-10-20(18)33-17(2)35)12-11-24(41-4)31-22-13-19-21(40-3)14-30(38,32(22,39)25(19)42-5)29(37,27(31)34)15-23(28)31/h7-10,19,21-25,27,37-39H,6,11-16H2,1-5H3,(H,33,35)/t19-,21+,22+,23-,24+,25+,27?,28-,29?,30+,31?,32+/m1/s1

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Solubility: Soluble in DMSO

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 ^oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥360 days if stored properly.

Stock Solution Storage: 0 - 4 ^oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

References:

1. Nie J, et al. Assessment of in vitro cardiotoxicity of extract fractions and diterpene alkaloids from Aconitum leucostomum Worosch: A short communication. J Pharm Biomed Anal. 2017 Apr 15;137:84-89.

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