Catalog No. Size 价格库存数量
S0208-2 2mg solid ¥535
S0208-10 10mg solid ¥2,140


CDC801 is a potent and orally active phosphodiesterase 4 (PDE4) and tumor necrosis factor-α (TNF-α) inhibitor with IC50 of 1.1 μM and 2.5 μM, respectively.

Product information

CAS Number: 192819-27-5

Molecular Weight: 408.45

Formula: C23H24N2O5

Chemical Name: 3-[3-(cyclopentyloxy)-4-methoxyphenyl]-3-(1, 3-dioxo-2, 3-dihydro-1H-isoindol-2-yl)propanamide

Smiles: COC1=CC=C(C=C1OC1CCCC1)C(CC(N)=O)N1C(=O)C2=CC=CC=C2C1=O


InChi: InChI=1S/C23H24N2O5/c1-29-19-11-10-14(12-20(19)30-15-6-2-3-7-15)18(13-21(24)26)25-22(27)16-8-4-5-9-17(16)23(25)28/h4-5,8-12,15,18H,2-3,6-7,13H2,1H3,(H2,24,26)

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Solubility: Soluble in DMSO

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥360 days if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

How to use

In Vitro:

The more detailed information refer to the Compound 6b in the reference 1 (PMID:19256507).


  1. Man HW, et al. Discovery of (S)-N-[2-[1-(3-ethoxy-4-methoxyphenyl)-2-methanesulfonylethyl]-1,3-dioxo-2,3-dihydro-1H-isoindol-4-yl] acetamide (apremilast), a potent and orally active phosphodiesterase 4and tumor necrosis factor-alpha inhibitor. J Med Chem. 2009 Mar 26;52(6):1522-4.

Products are for research use only. Not for human use.


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