Catalog No. Size 价格库存数量
S0206-2 2mg solid ¥320
售罄
不可用
S0206-10 10mg solid ¥1,280
售罄
不可用

详情描述

Negletein is a neuroprotectant enhances the action of nerve growth factor and induces neurite outgrowth in PC12 cells. Negletein shows promising anti-inflammatory activity via inhibition of TNF-α and IL-1β with IC50 values of 16.4 and 10.8 μM, respectively.

Product information

CAS Number: 29550-13-8

Molecular Weight: 284.26

Formula: C16H12O5

Chemical Name: 5, 6-dihydroxy-7-methoxy-2-phenyl-4H-chromen-4-one

Smiles: COC1=CC2OC(=CC(=O)C=2C(O)=C1O)C1C=CC=CC=1

InChiKey: ZTHLHHDJRXJGRX-UHFFFAOYSA-N

InChi: InChI=1S/C16H12O5/c1-20-13-8-12-14(16(19)15(13)18)10(17)7-11(21-12)9-5-3-2-4-6-9/h2-8,18-19H,1H3

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Solubility: Soluble in DMSO

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥360 days if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

References:

  1. Phan CW, et al. Negletein as a neuroprotectant enhances the action of nerve growth factor and induces neurite outgrowth in PC12 cells. Biofactors. 2016 Nov 12;42(6):591-599.
  2. Singh B, et al. Anti-inflammatory and immunomodulatory flavones from Actinocarya tibetica Benth.Nat Prod Res. 2013;27(23):2227-30.

Products are for research use only. Not for human use.

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