Desacetylcinobufotalin

Desacetylcinobufotalin is a natural compound; apoptosis inducer and shows the marked inhibition effect to HepG2 cells and the IC50 value is 0.0279μmol/ml.

Product information

CAS Number: 4099-30-3

Molecular Weight: 416.51

Formula: C24H32O6

Synonym:

Deacetylcinobufotalin

Chemical Name: 5-[(1R, 2S, 4R, 5R, 6R, 7R, 10S, 11R, 14S, 16S)-5, 14, 16-trihydroxy-7, 11-dimethyl-3-oxapentacyclo[8.8.0.0, .0, .0, ]octadecan-6-yl]-2H-pyran-2-one

Smiles: C[C@]12CC[C@H]3[C@@H](CC[C@]4(O)C[C@@H](O)CC[C@@]43C)[C@@]31O[C@@H]3[C@H](O)[C@@H]2C1C=CC(=O)OC=1

InChiKey: FRYICJTUIXEEGK-NNWVIVGYSA-N

InChi: InChI=1S/C24H32O6/c1-21-8-5-14(25)11-23(21,28)10-7-16-15(21)6-9-22(2)18(13-3-4-17(26)29-12-13)19(27)20-24(16,22)30-20/h3-4,12,14-16,18-20,25,27-28H,5-11H2,1-2H3/t14-,15-,16+,18-,19+,20+,21+,22+,23-,24+/m0/s1

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Solubility: DMSO : 100 mg/mL (240.09 mM; Need ultrasonic)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 ^oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥360 days if stored properly.

Stock Solution Storage: 0 - 4 ^oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

References:

1. The Effect and Mechanism of Apoptosis Induced by Desacetylcinobufotalin (DEBF) in Human Hepatocellular Carcinoma HepG2 Cells

Products are for research use only. Not for human use.