Catalog No. Size 价格库存数量
S0680-2 2mg solid ¥120
S0680-10 10mg solid ¥360


Bergenin is a cytoprotective and antioxidative polyphenol found in many medicinal plants. Bergenin has a wide spectrum activities such as hepatoprotective, antiinflammatory, immunomodulatory, antitumor, antiviral, and antifungal properties.

Product information

CAS Number: 477-90-7

Molecular Weight: 328.27

Formula: C14H16O9



Chemical Name: (2S, 4R, 5S, 6S, 7R)-5, 6, 12, 14-tetrahydroxy-4-(hydroxymethyl)-13-methoxy-3, 8-dioxatricyclo[, ]tetradeca-1(14), 10, 12-trien-9-one

Smiles: COC1=C(O)C=C2C(=O)O[C@H]3[C@@H](O[C@H](CO)[C@@H](O)[C@@H]3O)C2=C1O


InChi: InChI=1S/C14H16O9/c1-21-11-5(16)2-4-7(9(11)18)12-13(23-14(4)20)10(19)8(17)6(3-15)22-12/h2,6,8,10,12-13,15-19H,3H2,1H3/t6-,8-,10+,12+,13-/m1/s1

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Solubility: DMSO : ≥ 100 mg/mL (304.63 mM)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥360 days if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

How to use

In Vitro:

Bergenin (7.5-30µM; 24 hours) decreases the viability of HeLa cervical cancer cells (IC50=15 µM). Bergenin (7.5-30 µM; 24 hours) induces apoptosis in HeLa cervical cancer cells.

In Vivo:

Pretreatment with Bergenin (12.5-100 mg/kg; i.p.; once) produces a dose-related inhibition of acetic acid-induced writhing in mice.


  1. Shi X, et al. Anticancer activity of bergenin against cervical cancer cells involves apoptosis, cell cycle arrest, inhibition of cell migration and the STAT3 signalling pathway. Exp Ther Med. 2019 May;17(5):3525-3529.
  2. Yun J, et al. Bergenin decreases the morphine-induced physical dependence via antioxidative activity in mice. Arch Pharm Res. 2015 Jun;38(6):1248-54.
  3. de Oliveira CM, et al. Antinociceptive properties of bergenin. J Nat Prod. 2011 Oct 28;74(10):2062-8.

Products are for research use only. Not for human use.


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