Levistolide A

Levistolide A (LA), a natural compound isolated from the traditional Chinese herb Ligusticum chuanxiong Hort, is used for treating cancer. Levistolide A can induce apoptosis via ROS-mediated ER stress pathway.

Product information

CAS Number: 88182-33-6

Molecular Weight: 380.48

Formula: C24H28O4

Chemical Name: (1S, 2S, 6Z, 10S, 11S, 16Z)-6, 16-dibutylidene-5, 15-dioxapentacyclo[9.5.2.0, .0, .0, ]octadeca-3(7), 12-diene-4, 14-dione

Smiles: CCC/C=C1\OC(=O)C2[C@H]3[C@@H](CCC=2\1)[C@@H]1CC[C@]23C(=C1)C(=O)O/C/2=C\CCC

InChiKey: UBBRXVRQZJSDAK-ZJHGLIIDSA-N

InChi: InChI=1S/C24H28O4/c1-3-5-7-18-16-10-9-15-14-11-12-24(21(15)20(16)23(26)27-18)17(13-14)22(25)28-19(24)8-6-4-2/h7-8,13-15,21H,3-6,9-12H2,1-2H3/b18-7-,19-8-/t14-,15+,21-,24+/m1/s1

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Solubility: DMSO : 250 mg/mL (657.06 mM; Need ultrasonic)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 ^oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥360 days if stored properly.

Stock Solution Storage: 0 - 4 ^oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

References:

1. Yang Y,et al. Levistolide A Induces Apoptosis via ROS-Mediated ER Stress Pathway in Colon Cancer Cells. Cell Physiol Biochem 2017;42:929-938.

Products are for research use only. Not for human use.