RGD peptide (GRGDNP) (TFA)


Catalog No. Size 价格库存数量
S0827-2 2mg solid ¥330
S0827-10 10mg solid ¥1,320


RGD peptide (GRGDNP) (TFA) acts as an inhibitor of integrin-ligand interactions and plays an important role in cell adhesion, migration, growth, and differentiation. RGD peptide (GRGDNP) (TFA) promote apoptosis through activation of conformation changes that enhance pro-caspase-3 activation and autoprocessing.

Product information

Molecular Weight: 728.63

Formula: C25H39F3N10O12

Chemical Name: (S)-1-((6S, 12S, 15S)-1, 1-diamino-15-(2-amino-2-oxoethyl)-6-(2-aminoacetamido)-12-(carboxymethyl)-7, 10, 13-trioxo-2, 8, 11, 14-tetraazahexadec-1-ene)pyrrolidine-2-carboxylic acid compound with 2, 2, 2-trifluoroacetic acid (1:1)

Smiles: NC(N)=NCCC[C@H](NC(=O)CN)C(=O)NCC(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CC(N)=O)C(=O)N1CCC[C@H]1C(O)=O.OC(=O)C(F)(F)F


InChi: InChI=1S/C23H38N10O10.C2HF3O2/c24-9-16(35)30-11(3-1-5-28-23(26)27)19(39)29-10-17(36)31-12(8-18(37)38)20(40)32-13(7-15(25)34)21(41)33-6-2-4-14(33)22(42)43;3-2(4,5)1(6)7/h11-14H,1-10,24H2,(H2,25,34)(H,29,39)(H,30,35)(H,31,36)(H,32,40)(H,37,38)(H,42,43)(H4,26,27,28);(H,6,7)/t11-,12-,13-,14-;/m0./s1

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Solubility: DMSO : ≥ 50 mg/mL (68.62 mM)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥360 days if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200


  1. Ruoslahti, E., and Öbrink, B. Common principles in cell adhesion Experimental Cell Research 227, 1-11 (1996).
  2. Meredith JE Jr, et al. Integrins, adhesion and apoptosis. Trends Cell Biol. 1997 Apr;7(4):146-50.
  3. Yang W, et al. Activation of the Cdc42-associated tyrosine kinase-2 (ACK-2) by cell adhesion via integrin beta1. J Biol Chem. 1999 Mar 26;274(13):8524-30.

Products are for research use only. Not for human use.


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