FX-11

FX-11 (LDHA Inhibitor FX11) is a potent lactate dehydrogenase A (LDHA) inhibitor with an IC50 of 23.3 μM for HeLa cell and a Ki value of 8 μM.

Product information

CAS Number: 213971-34-7

Molecular Weight: 350.41

Formula: C22H22O4

Synonym:

LDHA Inhibitor FX11

Chemical Name: 7-benzyl-2, 3-dihydroxy-6-methyl-4-propylnaphthalene-1-carboxylic acid

Smiles: CC1=CC2=C(C=C1CC1C=CC=CC=1)C(C(O)=O)=C(O)C(O)=C2CCC

InChiKey: LVPYVYFMCKYFCZ-UHFFFAOYSA-N

InChi: InChI=1S/C22H22O4/c1-3-7-16-17-10-13(2)15(11-14-8-5-4-6-9-14)12-18(17)19(22(25)26)21(24)20(16)23/h4-6,8-10,12,23-24H,3,7,11H2,1-2H3,(H,25,26)

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Solubility: DMSO : 250 mg/mL (713.45 mM; Need ultrasonic)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 ^oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥360 days if stored properly.

Stock Solution Storage: 0 - 4 ^oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

References:

1. EMILIA C. CALVARESI, et al. SMALL MOLECULE INHIBITORS OF LACTATE DEHYDROGENASE A AS AN ANTICANCER STRATEGY.

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