Juglanin

Juglanin, a natural occurring flavonoid, is a JNK acticator, with inflammation and anti-tumor activities. Juglanin can induce apoptosis and autophagy on human breast cancer cells.

Product information

CAS Number: 5041-67-8

Molecular Weight: 418.35

Formula: C20H18O10

Chemical Name: 3-{[(2S, 3R, 4R, 5S)-3, 4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]oxy}-5, 7-dihydroxy-2-(4-hydroxyphenyl)-4H-chromen-4-one

Smiles: OC[C@@H]1O[C@@H](OC2C(=O)C3=C(C=C(O)C=C3O)OC=2C2C=CC(O)=CC=2)[C@H](O)[C@H]1O

InChiKey: POQICXMTUPVZMX-UXYNSRGZSA-N

InChi: InChI=1S/C20H18O10/c21-7-13-15(25)17(27)20(29-13)30-19-16(26)14-11(24)5-10(23)6-12(14)28-18(19)8-1-3-9(22)4-2-8/h1-6,13,15,17,20-25,27H,7H2/t13-,15-,17+,20-/m0/s1

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Solubility: Soluble in DMSO

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 ^oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥360 days if stored properly.

Stock Solution Storage: 0 - 4 ^oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

References:

1. Sun ZL, et al. Juglanin induces apoptosis and autophagy in human breast cancer progression via ROS/JNK promotion. Biomed Pharmacother. 2017 Jan;85:303-312.

Products are for research use only. Not for human use.