Baicalein Trimethyl Ether

5, 6, 7-Trimethoxyflavone is a novel p38-α MAPK inhibitor with an anti-inflammatory effect. 5, 6, 7-Trimethoxyflavone is isolated from several plants including Zeyhera tuberculosa, Callicarpa japonica, and Kickxia lanigera.

Product information

CAS Number: 973-67-1

Molecular Weight: 312.32

Formula: C18H16O5

Synonym:

Baicalein trimethyl ether

Chemical Name: 5, 6, 7-trimethoxy-2-phenyl-4H-chromen-4-one

Smiles: COC1=C(OC)C2C(=O)C=C(OC=2C=C1OC)C1C=CC=CC=1

InChiKey: HJNJAUYFFFOFBW-UHFFFAOYSA-N

InChi: InChI=1S/C18H16O5/c1-20-15-10-14-16(18(22-3)17(15)21-2)12(19)9-13(23-14)11-7-5-4-6-8-11/h4-10H,1-3H3

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Solubility: Soluble in DMSO

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 ^oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 ^oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

References:

1. Hassan AHE, et al. Repurposing mosloflavone/5, 6, 7-trimethoxyflavone-resveratrol hybrids: Discovery of novel p38-α MAPK inhibitors as potent interceptors of macrophage-dependent production of proinflammatory mediators. Eur J Med Chem. 2019 Jul 9;180:253-267.

Products are for research use only. Not for human use.