Mal-amido-PEG2-C2-acid

Mal-amido-PEG2-C2-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

Product information

CAS Number: 756525-98-1

Molecular Weight: 328.32

Formula: C14H20N2O7

Chemical Name: 3-(2-{2-[3-(2, 5-dioxo-2, 5-dihydro-1H-pyrrol-1-yl)propanamido]ethoxy}ethoxy)propanoic acid

Smiles: OC(=O)CCOCCOCCNC(=O)CCN1C(=O)C=CC1=O

InChiKey: GBPJQBDDYXDSNH-UHFFFAOYSA-N

InChi: InChI=1S/C14H20N2O7/c17-11(3-6-16-12(18)1-2-13(16)19)15-5-8-23-10-9-22-7-4-14(20)21/h1-2H,3-10H2,(H,15,17)(H,20,21)

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Solubility: Soluble in DMSO.

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 ^oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥360 days if stored properly.

Stock Solution Storage: 0 - 4 ^oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

References:

1. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562.

Products are for research use only. Not for human use.