详情描述
Mal-amido-PEG2-C2-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.
Product information
CAS Number: 756525-98-1
Molecular Weight: 328.32
Formula: C14H20N2O7
Chemical Name: 3-(2-{2-[3-(2, 5-dioxo-2, 5-dihydro-1H-pyrrol-1-yl)propanamido]ethoxy}ethoxy)propanoic acid
Smiles: OC(=O)CCOCCOCCNC(=O)CCN1C(=O)C=CC1=O
InChiKey: GBPJQBDDYXDSNH-UHFFFAOYSA-N
InChi: InChI=1S/C14H20N2O7/c17-11(3-6-16-12(18)1-2-13(16)19)15-5-8-23-10-9-22-7-4-14(20)21/h1-2H,3-10H2,(H,15,17)(H,20,21)
Technical Data
Appearance: Solid Power
Purity: ≥98% (or refer to the Certificate of Analysis)
Solubility: Soluble in DMSO.
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life: ≥360 days if stored properly.
Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.
Drug Formulation: To be determined
HS Tariff Code: 382200
References:
- An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562.
Products are for research use only. Not for human use.