Cl-C6-PEG4-O-CH2COOH

Cl-C6-PEG4-O-CH2COOH (PROTAC Linker 4) is a PEG-based PROTAC linker can be used in the synthesis of chloroalkane-containing PROTACs (HaloPROTACs).

Product information

CAS Number: 1799506-30-1

Molecular Weight: 370.87

Formula: C16H31ClO7

Synonym:

PROTAC Linker 4

Chemical Name: 21-chloro-3, 6, 9, 12, 15-pentaoxahenicosanoic acid

Smiles: OC(=O)COCCOCCOCCOCCOCCCCCCCl

InChiKey: JKRQJQUHILRKGV-UHFFFAOYSA-N

InChi: InChI=1S/C16H31ClO7/c17-5-3-1-2-4-6-20-7-8-21-9-10-22-11-12-23-13-14-24-15-16(18)19/h1-15H2,(H,18,19)

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Solubility: Ethanol : 100 mg/mL (269.64 mM; Need ultrasonic)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 ^oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥360 days if stored properly.

Stock Solution Storage: 0 - 4 ^oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

References:

1. Buckley DL, et al. HaloPROTACS: Use of Small Molecule PROTACs to Induce Degradation of HaloTag Fusion Proteins. ACS Chem Biol. 2015 Aug 21;10(8):1831-7.

Products are for research use only. Not for human use.