N33-TEG-COOH

N33-TEG-COOH (N3-TEG-COOH) is a PEG-based PROTAC linker can be used in the synthesis of PROTACs.

Product information

CAS Number: 201467-81-4

Molecular Weight: 277.27

Formula: C10H19N3O6

Synonym:

N3-TEG-COOH

14-Azido-3,6,9,12-tetraoxatetradecanoic acid

Chemical Name: 14-azido-3, 6, 9, 12-tetraoxatetradecanoic acid

Smiles: [N-]=[N+]=NCCOCCOCCOCCOCC(O)=O

InChiKey: YHTABJLSZLHRFV-UHFFFAOYSA-N

InChi: InChI=1S/C10H19N3O6/c11-13-12-1-2-16-3-4-17-5-6-18-7-8-19-9-10(14)15/h1-9H2,(H,14,15)

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Solubility: Ethanol : 100 mg/mL (360.66 mM; Need ultrasonic) DMSO : ≥ 100 mg/mL (360.66 mM)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 ^oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥360 days if stored properly.

Stock Solution Storage: 0 - 4 ^oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

References:

1. Zengerle M, et al. Selective Small Molecule Induced Degradation of the BET Bromodomain Protein BRD4. ACS Chem Biol. 2015 Aug 21;10(8):1770-7.

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