Thalidomide 4'-ether-alkylC8-amine

Thalidomide 4'-ether-alkylC8-amine is a functionalized cereblon ligand for PROTAC® research and development; incorporates an E3 ligase ligand plus an alkylC8 linker with a terminal amine ready for conjugation to a target protein ligand. Part of a range of functionalized tool molecules for PROTAC R&D.

Product information

CAS Number: 2636798-38-2

Molecular Weight: 437.92

Formula: C21H28ClN3O5

Synonym:

WUN-98382

Chemical Name: 4-[(8-Aminooctyl)oxy]-2-(2, 6-dioxo-3-piperidinyl)-1H-isoindole-1, 3(2H)-dione hydrochloride

Smiles: Cl.NCCCCCCCCOC1=CC=CC2=C1C(=O)N(C1CCC(=O)NC1=O)C2=O

InChiKey: WNWBISFFTQAOHN-UHFFFAOYSA-N

InChi: InChI=1S/C21H27N3O5.ClH/c22-12-5-3-1-2-4-6-13-29-16-9-7-8-14-18(16)21(28)24(20(14)27)15-10-11-17(25)23-19(15)26;/h7-9,15H,1-6,10-13,22H2,(H,23,25,26);1H

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Solubility: Soluble in DMSO

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 ^oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 ^oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

Products are for research use only. Not for human use.