Pomalidomide 4'-PEG4-azide


Catalog No. Size 价格库存数量
S1343-2 2mg solid ¥90
S1343-10 10mg solid ¥270


Pomalidomide 4'-PEG4-azide is a functionalized cereblon ligand for PROTAC® research and development; incorporates an E3 ligase ligand plus a PEG4 linker with terminal azide ready for conjugation to a target protein ligand. Part of a range of functionalized tool molecules for PROTAC R&D.

Product information

CAS Number: 2271036-47-4

Molecular Weight: 518.52

Formula: C23H30N6O8

Chemical Name: 4-[(14-Azido-3, 6, 9, 12-tetraoxatetradec-1-yl)amino]-2-(2, 6-dioxo-3-piperidinyl)-1H-isoindole-1, 3(2H)-dione



InChi: InChI=1S/C23H30N6O8/c24-28-26-7-9-35-11-13-37-15-14-36-12-10-34-8-6-25-17-3-1-2-16-20(17)23(33)29(22(16)32)18-4-5-19(30)27-21(18)31/h1-3,18,25H,4-15H2,(H,27,30,31)

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Solubility: DMSO : 33.33 mg/mL (64.28 mM; Need ultrasonic)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥360 days if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

How to use

In Vitro:

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.


  1. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Products are for research use only. Not for human use.


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