详情描述
RPN77612 is a synthetic curcuminoid molecule with multiple bio-actvities, including (1) cytotoxic effect on HeLa, K562, MCF-7 and MDA-MB-231 cancer cell lines; (2) ameliorating amyloid precursor protein (APP) and tau protein pathology and rescues cognitive deficits in neurodegenerative diseases; (3) inhibitor of transcription factor NF-κB and activators of Nrf2 and uses thereof for treatment of neurological disoders and inflammatory diseases.
Product information
CAS Number: 39777-61-2
Molecular Weight: 294.34
Formula: C19H18O3
Chemical Name: (1E, 4E)-1, 5-Bis(2-methoxyphenyl)penta-1, 4-dien-3-one
Smiles: COC1=CC=CC=C1/C=C/C(=O)/C=C/C1=CC=CC=C1OC
InChiKey: RCZMPCUUTSDNAJ-PHEQNACWSA-N
InChi: InChI=1S/C19H18O3/c1-21-18-9-5-3-7-15(18)11-13-17(20)14-12-16-8-4-6-10-19(16)22-2/h3-14H,1-2H3/b13-11+,14-12+
Technical Data
Appearance: Solid Power
Purity: ≥98% (or refer to the Certificate of Analysis)
Solubility: Soluble in DMSO
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life: ≥360 days if stored properly.
Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.
Drug Formulation: To be determined
HS Tariff Code: 382200
Products are for research use only. Not for human use.