VUN34002

VUN34002, also known as Vanin-1-IN-1 is an inhibitor of vanin-1 enzyme which is a cell surface associated, giycosyiphosphatidyS inositol (GPi) anchored protein and plays an important role in metabolism and inflammation.

Product information

CAS Number: 2173134-00-2

Molecular Weight: 354.41

Formula: C18H22N6O2

Synonym:

Vanin-1-IN-1

Chemical Name: (2-((pyrazin-2-ylmethyl)amino)pyrimidin-5-yl)(8-oxa-2-azaspiro[4.5]decan-2-yl)methanone

Smiles: O=C(C1=CN=C(NCC2=CN=CC=N2)N=C1)N1CC2(CC1)CCOCC2

InChiKey: VGRLXWFIXGZRMS-UHFFFAOYSA-N

InChi: InChI=1S/C18H22N6O2/c25-16(24-6-1-18(13-24)2-7-26-8-3-18)14-9-21-17(22-10-14)23-12-15-11-19-4-5-20-15/h4-5,9-11H,1-3,6-8,12-13H2,(H,21,22,23)

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Solubility: DMSO: 125 mg/mL (352.70 mM)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 ^oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥360 days if stored properly.

Stock Solution Storage: 0 - 4 ^oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

References:

1. Agustin Casimiro-Garcia, et al. Novel pyrimidine carboxamides as inhibitors of vanin-1 enzyme. WO2018011681A1.

Products are for research use only. Not for human use.