详情描述
Hydralazine Hydrochloride is a direct-acting vasodilator that is used as an antihypertensive agent. Hydralazine Hydrochloride alters intracellular calcium release and interferes with smooth muscle cell calcium influx, resulting in arterial vasodilatation. This agent also inhibits the phosphorylation of myosin protein and chelation of trace metals required for smooth muscle contraction, resulting in an increase in heart rate, stroke volume and cardiac output. In addition to its cardiovascular effects, hydralazine inhibits DNA methyltransferase, which may result in inhibition of DNA methylation in tumor cells.
Product information
CAS Number: 304-20-1
Molecular Weight: 196.64
Formula: C8H9ClN4
Chemical Name: 1-hydrazinylidene-1,2-dihydrophthalazine hydrochloride
Smiles: Cl.NN=c1[nH][n]cc2ccccc12
InChiKey: ZUXNZUWOTSUBMN-UHFFFAOYSA-N
InChi: InChI=1S/C8H8N4.ClH/c9-11-8-7-4-2-1-3-6(7)5-10-12-8;/h1-5H,9H2,(H,11,12);1H
Technical Data
Appearance: Solid Power
Purity: ≥98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life: ≥360 days if stored properly.
Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.
Drug Formulation: To be determined
HS Tariff Code: 382200
Products are for research use only. Not for human use.