Catalog No. Size 价格库存数量
S1680-2 Solid 2 mg ¥115
S1680-10 Solid 10 mg ¥345


EG-00229 trifluoroacetate is a Neuropilin 1 (NRP1) receptor antagonist which inhibits the binding of VEGFA to the NRP1 b1 domain. EG-00229 TFA has no effect on the binding of VEGFA to VEGFR-1 and VEGFR-2. EG-00229 TFA reduces VEGFA-induced VEGFR-2 tyrosine phosphorylation, attenuates VEGFA-induced HUVEC cell migration, and reduces A549 lung carcinoma cell viability in vitro.

Product information

CAS Number: 1210945-69-9

Molecular Weight: 611.60

Formula: C19H20F3N7O7S3

Chemical Name: (2S)-2-{[3-(2,1,3-benzothiadiazole-4-sulfonamido)thiophen-2-yl]formamido}-5-[(diaminomethylidene)amino]pentanoic acid; trifluoroacetic acid

Smiles: NC(N)=NCCC[C@H](NC(=O)C1SC=CC=1NS(=O)(=O)C1=CC=CC2=NSN=C21)C(O)=O.OC(=O)C(F)(F)F


InChi: InChI=1S/C17H19N7O5S3.C2HF3O2/c18-17(19)20-7-2-4-11(16(26)27)21-15(25)14-10(6-8-30-14)24-32(28,29)12-5-1-3-9-13(12)23-31-22-9;3-2(4,5)1(6)7/h1,3,5-6,8,11,24H,2,4,7H2,(H,21,25)(H,26,27)(H4,18,19,20);(H,6,7)/t11-;/m0./s1

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥360 days if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

Products are for research use only. Not for human use.


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