Catalog No. Size 价格库存数量
S1794-2 Solid 2 mg ¥125
S1794-10 Solid 10 mg ¥375


RO-9187 is a potent inhibitor of HCV virus replication in the replicon system (IC(50) = 171 +/- 12 nM; CC(50) >1 mM). RO-9187 is an excellent substrate for deoxycytidine kinase and is phosphorylated with efficiencies up to 3-fold higher than deoxycytidine. RO-9187 is a new class of antiviral nucleosides with promising preclinical properties as potential medicines for the treatment of HCV infection.

Product information

CAS Number: 876708-03-1

Molecular Weight: 284.23

Formula: C9H12N6O5

Chemical Name: 4-amino-1-[(2R,3S,4S,5R)-5-azido-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-1,2-dihydropyrimidin-2-one

Smiles: [N-]=[N+]=N[C@]1(CO)O[C@H]([C@@H](O)[C@@H]1O)N1C=CC(N)=NC1=O


InChi: InChI=1S/C9H12N6O5/c10-4-1-2-15(8(19)12-4)7-5(17)6(18)9(3-16,20-7)13-14-11/h1-2,5-7,16-18H,3H2,(H2,10,12,19)/t5-,6-,7+,9+/m0/s1

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥360 days if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

Products are for research use only. Not for human use.


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