详情描述
D-609, also known as D-609 free, is a phospholipase C inhibitor potentially for the treatment of pancreatic cancer. D-609, an inhibitor of PC-PLC and sphingomyelin synthase, strongly inhibited myogenic tone and had no effect on depolarization-induced contraction. D-609 appeared to act by lowering cytoplasmic Ca(2+) concentration to levels below those that activate contraction.
Product information
CAS Number: 83373-60-8
Molecular Weight: 266.46
Formula: C11H15KOS2
Chemical Name: potassium ({tricyclo[5.2.1.0²,⁶]decan-8-yloxy}methanethioyl)sulfanide
Smiles: [K+].[S-]C(=S)OC1CC2CC1C1CCCC21
InChiKey: IGULCCCBGBDZKQ-UHFFFAOYSA-M
InChi: InChI=1S/C11H16OS2.K/c13-11(14)12-10-5-6-4-9(10)8-3-1-2-7(6)8;/h6-10H,1-5H2,(H,13,14);/q;+1/p-1
Technical Data
Appearance: Solid Power
Purity: ≥98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life: ≥360 days if stored properly.
Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.
Drug Formulation: To be determined
HS Tariff Code: 382200
Products are for research use only. Not for human use.