CC-401 Hydrochloride


Catalog No. Size 价格库存数量
S1944-2 Solid 2 mg ¥105
S1944-10 Solid 10 mg ¥315


CC-401, also known as JNK-401, is a potent, selective, ATP-competitive pan-JNK inhibitor that decreases hepatic necrosis and apoptosis, significantly reduces tubular apoptosis in the obstructed kidney, sensitizes hypoxic colon cancer cells to DNA-damaging agents, and potentiates the effect of bevacizumab and oxaliplatin in HT29-derived mouse xenografts. CC-401 Promotes β-Cell Replication via Pleiotropic Consequences of DYRK1A/B Inhibition.

Product information

CAS Number: 1438391-30-0

Molecular Weight: 424.93

Formula: C22H25ClN6O

Chemical Name: 3-{3-[2-(piperidin-1-yl)ethoxy]phenyl}-5-(1H-1,2,4-triazol-5-yl)-1H-indazole hydrochloride

Smiles: Cl.C(CN1CCCCC1)OC1=CC(=CC=C1)C1=NNC2=CC=C(C=C21)C1NN=CN=1


InChi: InChI=1S/C22H24N6O.ClH/c1-2-9-28(10-3-1)11-12-29-18-6-4-5-16(13-18)21-19-14-17(22-23-15-24-27-22)7-8-20(19)25-26-21;/h4-8,13-15H,1-3,9-12H2,(H,25,26)(H,23,24,27);1H

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥360 days if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

Products are for research use only. Not for human use.


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