Catalog No. Size 价格库存数量
S1966-2 Solid 2 mg ¥105
S1966-10 Solid 10 mg ¥315


Ko-143 is a potent and selective breast cancer resistance protein multidrug transporter (BCRP) inhibitor (EC90 = 26 nM). Ko-143 is a nontoxic analog of fungal toxin fumitremorgin C, is a potent inhibitor of ABCG2.

Product information

CAS Number: 461054-93-3

Molecular Weight: 469.57

Formula: C26H35N3O5

Chemical Name: tert-butyl 3-[(2S,5S,8S)-14-methoxy-2-(2-methylpropyl)-4,7-dioxo-3,6,17-triazatetracyclo[³,⁸.0¹¹,¹⁶]heptadeca-1(10),11(16),12,14-tetraen-5-yl]propanoate

Smiles: CC(C)C[C@H]1C2NC3=CC(=CC=C3C=2C[C@H]2C(=O)N[C@@H](CCC(=O)OC(C)(C)C)C(=O)N21)OC


InChi: InChI=1S/C26H35N3O5/c1-14(2)11-20-23-17(16-8-7-15(33-6)12-19(16)27-23)13-21-24(31)28-18(25(32)29(20)21)9-10-22(30)34-26(3,4)5/h7-8,12,14,18,20-21,27H,9-11,13H2,1-6H3,(H,28,31)/t18-,20-,21-/m0/s1

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥360 days if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

Products are for research use only. Not for human use.


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