gamma-secretase modulator 2


Catalog No. Size 价格库存数量
S1974-2 Solid 2 mg ¥140
S1974-10 Solid 10 mg ¥420


gamma-secretase modulator 2 is a potent and selective γ-secretase modulator for treatment of Alzheimer's disease. γ-secretaseγ-secretase modulator is modulation of the action of γ-secretase so as to Selectively attenuate production of Aβ(1-42) and hence find use in treatment or prevention of diseases associated with deposition of Aβ in the brain. γ-secretase modulator is usful in particular Alzheimer’s disease.

Product information

CAS Number: 1093978-89-2

Molecular Weight: 514.47

Formula: C25H22F4N6O2

Chemical Name: 6-fluoro-3-{4-[3-methoxy-4-(4-methyl-1H-imidazol-1-yl)phenyl]-1H-1,2,3-triazol-1-yl}-1-(2,2,2-trifluoroethyl)-2,3,4,5-tetrahydro-1H-1-benzazepin-2-one

Smiles: CC1=CN(C=N1)C1=CC=C(C=C1OC)C1=CN(N=N1)C1CCC2=C(C=CC=C2F)N(CC(F)(F)F)C1=O


InChi: InChI=1S/C25H22F4N6O2/c1-15-11-33(14-30-15)21-8-6-16(10-23(21)37-2)19-12-35(32-31-19)22-9-7-17-18(26)4-3-5-20(17)34(24(22)36)13-25(27,28)29/h3-6,8,10-12,14,22H,7,9,13H2,1-2H3

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥360 days if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

Products are for research use only. Not for human use.


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