Plerixafor (octahydrochloride)

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Catalog No. Size 价格库存数量
S1982-2 Solid 2 mg ¥85
售罄
不可用
S1982-10 Solid 10 mg ¥255
售罄
不可用

详情描述

Plerixafor, also known as AMD3100, is a bicyclam with hematopoietic stem cell-mobilizing activity. Plerixafor blocks the binding of stromal cell-derived factor (SDF-1alpha) to the cellular receptor CXCR4, resulting in hematopoietic stem cell (HSC) release from bone marrow and HSC movement into the peripheral circulation. Check for active clinical trials or closed clinical trials using this agent. (NCI Thesaurus). Plerixafor was approved by the U.S. Food and Drug Administration for this indication on December 15, 2008. In Europe, the drug was approved on 29 May 2009.

Product information

CAS Number: 155148-31-5

Molecular Weight: 794.47

Formula: C28H62Cl8N8

Chemical Name: 1-({4-[(1,4,8,11-tetraazacyclotetradecan-1-yl)methyl]phenyl}methyl)-1,4,8,11-tetraazacyclotetradecane octahydrochloride

Smiles: Cl.Cl.Cl.Cl.Cl.Cl.Cl.Cl.C(C1C=CC(CN2CCNCCCNCCNCCC2)=CC=1)N1CCNCCCNCCNCCC1

InChiKey: UEUPDYPUTTUXLJ-UHFFFAOYSA-N

InChi: InChI=1S/C28H54N8.8ClH/c1-9-29-15-17-31-13-3-21-35(23-19-33-11-1)25-27-5-7-28(8-6-27)26-36-22-4-14-32-18-16-30-10-2-12-34-20-24-36;;;;;;;;/h5-8,29-34H,1-4,9-26H2;8*1H

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥360 days if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

Products are for research use only. Not for human use.

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