详情描述
Fiacitabine, also known as FIAC or DRG-0077, is a pyrimidine nucleoside analog reported to elicit potent anti-VZV activity both in vitro and in vivo. Fiacitabine has potent antiviral activity in vivo against herpes simplex virus types 1 and 2 and cytomegalovirus. Fiacitabine is therapeutically superior to ara-A for the treatment of varicella-zoster virus infections in immunosuppressed subjects.
Product information
CAS Number: 69123-90-6
Molecular Weight: 371.10
Formula: C9H11FIN3O4
Chemical Name: 4-amino-1-[(2R,3S,4R,5R)-3-fluoro-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-iodo-1,2-dihydropyrimidin-2-one
Smiles: NC1=NC(=O)N(C=C1I)[C@@H]1O[C@H](CO)[C@@H](O)[C@@H]1F
InChiKey: GIMSJJHKKXRFGV-BYPJNBLXSA-N
InChi: InChI=1S/C9H11FIN3O4/c10-5-6(16)4(2-15)18-8(5)14-1-3(11)7(12)13-9(14)17/h1,4-6,8,15-16H,2H2,(H2,12,13,17)/t4-,5+,6-,8-/m1/s1
Technical Data
Appearance: Solid Power
Purity: ≥98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life: ≥360 days if stored properly.
Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.
Drug Formulation: To be determined
HS Tariff Code: 382200
Products are for research use only. Not for human use.