Catalog No. Size 价格库存数量
S1998-2 Solid 2 mg ¥175
S1998-10 Solid 10 mg ¥575


MK-0812 is a potent and selective CCR2 antagonist. Chemokine (C-C motif) receptor 2 (CCR2) is central for the migration of monocytes into inflamed tissues. The inhibition of CCR2 signaling represents a potential therapeutic approach for treatment of metastasis without affecting homeostatic functions.

Product information

CAS Number: 624733-88-6

Molecular Weight: 469.54

Formula: C24H34F3N3O3

Chemical Name: (3S,4S)-3-methoxy-N-[(1R,3S)-3-(propan-2-yl)-3-[3-(trifluoromethyl)-5,6,7,8-tetrahydro-1,6-naphthyridine-6-carbonyl]cyclopentyl]oxan-4-amine

Smiles: CC(C)[C@]1(C[C@@H](CC1)N[C@H]1CCOC[C@H]1OC)C(=O)N1CC2=CC(=CN=C2CC1)C(F)(F)F


InChi: InChI=1S/C24H34F3N3O3/c1-15(2)23(7-4-18(11-23)29-20-6-9-33-14-21(20)32-3)22(31)30-8-5-19-16(13-30)10-17(12-28-19)24(25,26)27/h10,12,15,18,20-21,29H,4-9,11,13-14H2,1-3H3/t18-,20+,21-,23+/m1/s1

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥360 days if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

Products are for research use only. Not for human use.


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