详情描述
KPT-185 is a selective and irreversible inhibitor of chromosome maintenance protein 1 (CRM1). CRM is an important nuclear protein export receptor. Blocking CRM1-mediated nuclear export can result in the suppression of tumors.
Product information
CAS Number: 1333151-73-7
Molecular Weight: 355.31
Formula: C16H16F3N3O3
Chemical Name: propan-2-yl (2Z)-3-{3-[3-methoxy-5-(trifluoromethyl)phenyl]-1H-1,2,4-triazol-1-yl}prop-2-enoate
Smiles: COC1C=C(C=C(C=1)C(F)(F)F)C1=NN(C=N1)/C=C\C(=O)OC(C)C
InChiKey: NLNGWFLRRRYNIL-PLNGDYQASA-N
InChi: InChI=1S/C16H16F3N3O3/c1-10(2)25-14(23)4-5-22-9-20-15(21-22)11-6-12(16(17,18)19)8-13(7-11)24-3/h4-10H,1-3H3/b5-4-
Technical Data
Appearance: Solid Power
Purity: ≥98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life: ≥360 days if stored properly.
Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.
Drug Formulation: To be determined
HS Tariff Code: 382200
Products are for research use only. Not for human use.