(Z)-2-decenoic acid

(Z)-2-decenoic acid (cis-2-Decenoic acid) is an unsaturated fatty acid produced by Pseudomonas aeruginosa. (Z)-2-decenoic acid induces a dispersion response in biofilms formed by a range of gram-negative bacteria, including P. aeruginosa, and by gram-positive bacteria. (Z)-2-decenoic acid inhibits biofilm development.

Product information

CAS Number: 15790-91-7

Molecular Weight: 170.25

Formula: C10H18O2

Synonym:

cis-2-Decenoic acid

Chemical Name: (2Z)-dec-2-enoic acid

Smiles: CCCCCCC/C=C\C(O)=O

InChiKey: WXBXVVIUZANZAU-HJWRWDBZSA-N

InChi: InChI=1S/C10H18O2/c1-2-3-4-5-6-7-8-9-10(11)12/h8-9H,2-7H2,1H3,(H,11,12)/b9-8-

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Solubility: DMSO : 250 mg/mL (1468.43 mM; Need ultrasonic)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 ^oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥360 days if stored properly.

Stock Solution Storage: 0 - 4 ^oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

How to use

In Vitro:

When added exogenously to P. aeruginosa PAO1 biofilms at a native concentration of 2.5 nM, (Z)-2-decenoic acid (cis-2-Decenoic acid) is shown to induce the dispersion of biofilm microcolonies.

References:

1. David G Davies, et al. A fatty acid messenger is responsible for inducing dispersion in microbial biofilms. J Bacteriol. 2009 Mar;191(5):1393-403.

Products are for research use only. Not for human use.