详情描述
Anguizole is a potent NS4B-AH2 inhibitor. Anguizole disrupts all of NS4B-AH2-mediated biological functions of NS4B. hronic hepatitis C virus (HCV) infection is responsible for severe liver diseases including liver cirrhosis and hepatocellular carcinoma. An HCV non-structural protein 4B (NS4B) plays an essential role in viral RNA genome replication by building multi-vesicular structures around endoplasmic reticulum membranes.
Product information
CAS Number: 442666-98-0
Molecular Weight: 408.81
Formula: C17H11ClF2N4O2S
Chemical Name: 7-(chlorodifluoromethyl)-5-(furan-2-yl)-N-[(thiophen-2-yl)methyl]pyrazolo[1,5-a]pyrimidine-2-carboxamide
Smiles: O=C(NCC1=CC=CS1)C1C=C2N=C(C=C(N2N=1)C(F)(F)Cl)C1=CC=CO1
InChiKey: GBNREAYNZPJROB-UHFFFAOYSA-N
InChi: InChI=1S/C17H11ClF2N4O2S/c18-17(19,20)14-7-11(13-4-1-5-26-13)22-15-8-12(23-24(14)15)16(25)21-9-10-3-2-6-27-10/h1-8H,9H2,(H,21,25)
Technical Data
Appearance: Solid Power
Purity: ≥98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life: ≥360 days if stored properly.
Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.
Drug Formulation: To be determined
HS Tariff Code: 382200
Products are for research use only. Not for human use.