详情描述
SMND-309 is a novel derivate of salvianolic acid B. SMND-309 promotes neuron survival through the activation of the PI3K/Akt/CREB-signalling pathway. SMND-309 protects rat brains ischemia and reperfusion injury by targeting the JAK2/STAT3 pathway. SMND-309 promotes angiogenesis in human umbilical vein endothelial cells through activating erythropoietin receptor/STAT3/VEGF pathways.
Product information
CAS Number: 1065559-56-9
Molecular Weight: 358.30
Formula: C18H14O8
Chemical Name: (2E)-2-[6-(2-carboxyeth-1-en-1-yl)-2,3-dihydroxyphenyl]-3-(3,4-dihydroxyphenyl)prop-2-enoic acid
Smiles: OC(=O)/C=C/C1=CC=C(O)C(O)=C1/C(=C\C1=CC(O)=C(O)C=C1)/C(O)=O
InChiKey: OAHRXWZJURTMHG-ACIWFXKJSA-N
InChi: InChI=1S/C18H14O8/c19-12-4-1-9(8-14(12)21)7-11(18(25)26)16-10(3-6-15(22)23)2-5-13(20)17(16)24/h1-8,19-21,24H,(H,22,23)(H,25,26)/b6-3+,11-7+
Technical Data
Appearance: Solid Power
Purity: ≥98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life: ≥360 days if stored properly.
Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.
Drug Formulation: To be determined
HS Tariff Code: 382200
Products are for research use only. Not for human use.