Catalog No. Size 价格库存数量
S2221-2 Solid 2 mg ¥80
S2221-10 Solid 10 mg ¥240


Alobresib, also known as GS-5829, is a potent and selective BET inhibitor. GS-5829 targets chronic lymphocytic leukemia cells and their supportive microenvironment. GS-5829 inhibited CLL cell proliferation and induced leukemia cell apoptosis through deregulation of key signaling pathways, such as BLK, AKT, ERK1/2, and MYC. IκBα modulation indicates that GS-5829 also inhibited NF-κB signaling. GS-5829-induced apoptosis resulted from an imbalance between positive (BIM) and negative regulators (BCL-XL) of the intrinsic apoptosis pathway.

Product information

CAS Number: 68-41-7

Molecular Weight: 102.09

Formula: C3H6N2O2

Chemical Name: (4R)-4-amino-1,2-oxazolidin-3-one

Smiles: N[C@@H]1CONC1=O


InChi: InChI=1S/C3H6N2O2/c4-2-1-7-5-3(2)6/h2H,1,4H2,(H,5,6)/t2-/m1/s1

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥360 days if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

Products are for research use only. Not for human use.


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