TG 100572 Hydrochloride

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Catalog No. Size 价格库存数量
S2232-2 Solid 2 mg ¥150
售罄
不可用
S2232-10 Solid 10 mg ¥450
售罄
不可用

详情描述

TG-100572 is a potent and selective VEGFR2/Src kinase inhibitor. TG100572 inhibits Src kinases and selected receptor tyrosine kinases, induced apoptosis of proliferating endothelial cells in vitro. TG100572 inhibits downstream molecules involved in the vascular endothelial growth factor (VEGF) signaling pathway resulted in markedly diminished levels of HSV-induced angiogenesis and significantly reduced the severity of SK lesions..

Product information

CAS Number: 867331-64-4

Molecular Weight: 512.43

Formula: C26H27Cl2N5O2

Chemical Name: 4-chloro-3-[5-methyl-3-({4-[2-(pyrrolidin-1-yl)ethoxy]phenyl}amino)-1,2,4-benzotriazin-7-yl]phenol hydrochloride

Smiles: Cl.CC1=CC(=CC2=NN=C(NC3C=CC(=CC=3)OCCN3CCCC3)N=C21)C1=CC(O)=CC=C1Cl

InChiKey: NVINBIHNVAYEND-UHFFFAOYSA-N

InChi: InChI=1S/C26H26ClN5O2.ClH/c1-17-14-18(22-16-20(33)6-9-23(22)27)15-24-25(17)29-26(31-30-24)28-19-4-7-21(8-5-19)34-13-12-32-10-2-3-11-32;/h4-9,14-16,33H,2-3,10-13H2,1H3,(H,28,29,31);1H

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥360 days if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

Products are for research use only. Not for human use.

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