Catalog No. Size 价格库存数量
S2236-2 Solid 2 mg ¥1,020
S2236-10 Solid 10 mg ¥4,080


Refametinib R enantiomer is a potent, selective and allosteric inhibitor of MEK1/2 in enzyme inhibition assays. Refametinib R has been reported to inhibit MEK activity and inhibit anchorage-dependent growth. Moreover, it has shown a potent tumor growth inhibition (TGI) in the human A375 and colon carcinoma Colo205 tumor xenograft models.

Product information

CAS Number: 923032-38-6

Molecular Weight: 572.34

Formula: C19H20F3IN2O5S


BAY 869766 R enantiomer

RDEA119 R enantiomer

RDEA-119 R enantiomer

BAY 86-9766 R enantiomer

Chemical Name: N-{3,4-difluoro-2-[(2-fluoro-4-iodophenyl)amino]-6-methoxyphenyl}-1-(2,3-dihydroxypropyl)cyclopropane-1-sulfonamide

Smiles: COC1=CC(F)=C(F)C(NC2=CC=C(I)C=C2F)=C1NS(=O)(=O)C1(CC(O)CO)CC1


InChi: InChI=1S/C19H20F3IN2O5S/c1-30-15-7-13(21)16(22)18(24-14-3-2-10(23)6-12(14)20)17(15)25-31(28,29)19(4-5-19)8-11(27)9-26/h2-3,6-7,11,24-27H,4-5,8-9H2,1H3

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥360 days if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

Products are for research use only. Not for human use.


Recently viewed