MK-4827 Hydrochloride

filler

Catalog No. Size 价格库存数量
S2281-2 Solid 2 mg ¥95
售罄
不可用
S2281-10 Solid 10 mg ¥285
售罄
不可用

详情描述

Niraparib, also know as MK-4827, is an inhibitor of poly (ADP-ribose) polymerase (PARP) with potential antineoplastic activity. MK4827 inhibits PARP activity, enhancing the accumulation of DNA strand breaks and promoting genomic instability and apoptosis. The PARP family of proteins detect and repair single strand DNA breaks by the base-excision repair (BER) pathway.

Product information

CAS Number: 1038915-64-8

Molecular Weight: 356.85

Formula: C19H21ClN4O

Chemical Name: 2-{4-[(3S)-piperidin-3-yl]phenyl}-2H-indazole-7-carboxamide hydrochloride

Smiles: Cl.NC(=O)C1=CC=CC2=CN(N=C21)C1C=CC(=CC=1)[C@H]1CNCCC1

InChiKey: YXYDNYFWAFBCAN-PFEQFJNWSA-N

InChi: InChI=1S/C19H20N4O.ClH/c20-19(24)17-5-1-3-15-12-23(22-18(15)17)16-8-6-13(7-9-16)14-4-2-10-21-11-14;/h1,3,5-9,12,14,21H,2,4,10-11H2,(H2,20,24);1H/t14-;/m1./s1

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥360 days if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

Products are for research use only. Not for human use.

相似产品

Recently viewed