详情描述
Rivastigmine, also known as ENA-713, is a carbamate-derived reversible cholinesterase inhibitor that is selective for the central nervous system and is used for the treatment of Dementia, Alzheimer's Disease and Parkinson's Disease. It acts by covalently modifying a serine residue in the active site by carbamoylation, as it stabilizes or reduces the rate of decline in certain cognitive functions.
Product information
CAS Number: 129101-54-8
Molecular Weight: 400.42
Formula: C18H28N2O8
Chemical Name: (2R,3R)-2,3-dihydroxybutanedioic acid; 3-[(1S)-1-(dimethylamino)ethyl]phenyl N-ethyl-N-methylcarbamate
Smiles: CN(C)[C@@H](C)C1=CC(=CC=C1)OC(=O)N(C)CC.O[C@H]([C@@H](O)C(O)=O)C(O)=O
InChiKey: GWHQHAUAXRMMOT-MBANBULQSA-N
InChi: InChI=1S/C14H22N2O2.C4H6O6/c1-6-16(5)14(17)18-13-9-7-8-12(10-13)11(2)15(3)4;5-1(3(7)8)2(6)4(9)10/h7-11H,6H2,1-5H3;1-2,5-6H,(H,7,8)(H,9,10)/t11-;1-,2-/m01/s1
Technical Data
Appearance: Solid Power
Purity: ≥98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life: ≥360 days if stored properly.
Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.
Drug Formulation: To be determined
HS Tariff Code: 382200
Products are for research use only. Not for human use.