详情描述
TMC353121 is a a respiratory syncytial virus (RSV) fusion inhibitor as a candidate to treat human respiratory syncytial virus infection. TMC353121 exerted dose-dependent antiviral effect ranging from full inhibition to absence of antiviral activity, in a preclinical model highly permissive for RSV replication. Human respiratory syncytial virus (hRSV) is a significant cause of respiratory illness in at-risk pediatric patients, immunocompromised adults and the elderly.
Product information
CAS Number: 857066-90-1
Molecular Weight: 558.71
Formula: C32H42N6O3
Chemical Name: 2-{[6-({[2-(3-hydroxypropyl)-5-methylphenyl]amino}methyl)-2-{[3-(morpholin-4-yl)propyl]amino}-1H-1,3-benzodiazol-1-yl]methyl}-6-methylpyridin-3-ol
Smiles: CC1=CC(NCC2C=C3C(=CC=2)N=C(NCCCN2CCOCC2)N3CC2=NC(C)=CC=C2O)=C(CCCO)C=C1
InChiKey: DKORMNNYNRPTBJ-UHFFFAOYSA-N
InChi: InChI=1S/C32H42N6O3/c1-23-6-9-26(5-3-16-39)28(19-23)34-21-25-8-10-27-30(20-25)38(22-29-31(40)11-7-24(2)35-29)32(36-27)33-12-4-13-37-14-17-41-18-15-37/h6-11,19-20,34,39-40H,3-5,12-18,21-22H2,1-2H3,(H,33,36)
Technical Data
Appearance: Solid Power
Purity: ≥98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life: ≥360 days if stored properly.
Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.
Drug Formulation: To be determined
HS Tariff Code: 382200
Products are for research use only. Not for human use.